Genetic risk prediction and neurobiological understanding of alcoholism.

Transl Psychiatry · 2014 · PMC4035721 · PMID 24844177

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

a trend towards significanceP =0.053so close (0.05 < p ≤ 0.1)

nominally significantno p-value reported

A panel of all the nominally significant P -value SNPs in the top candidate genes discovered by CFG ( n =135 genes, 713 SNPs) was used to generate a genetic risk prediction score (GRPS), which showed a trend towards significance ( P =0.053) in separating alcohol dependent individuals from controls in an independent German test cohort.

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