Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice.

In response to the first injection of low-dose D-amphetamine (2.5 mg/kg, i.p.), the ChAT-ChR2-EYFP BAC transgenic mice showed a tendency for a greater locomotor response than their sibling controls, but this effect did not reach statistical significance (Figure 4A ).

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