Barely Significant
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The effect of rituximab therapy on immunoglobulin levels in patients with multisystem autoimmune disease.

BMC Musculoskelet Disord · 2014 · PMC4038057 · PMID 24884562

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Median IgG levels trended downwards in those who received >6 g rituximab, although this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.