Barely Significant
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Incomplete pneumolysin oligomers form membrane pores.

Open Biol · 2014 · PMC4043118 · PMID 24759615

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a clear trendno p-value reported
However, a clear trend seen in the partial pore and pore structures is that relatively less density is resolved skirting these structures than in the pre-pores that have full coverage of the inside of the oligomer by sealing lipid, and better membrane density is observed on one side of the oligomer rather than the other in several cases.

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