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Calcineurin inhibitors may be a reasonable alternative to cyclophosphamide in the induction treatment of active lupus nephritis: A systematic review and meta-analysis.

Exp Ther Med · 2014 · PMC4043578 · PMID 24926363

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However, patients receiving CNIs appeared to have a higher risk of experiencing a transient increase in SCr (RR=0.42; 95% CI 0.14–1.21) and glucose disorder (RR=0.75; 95%CI 0.37–1.51) though this did not reach statistical significance.

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