Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes.

PLoS One · 2014 · PMC4044035 · PMID 24892553

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borderline significantno p-value reported

In our hands, guanabenz markedly reduced the effects of tunicamycin on IRE1α, GRP78, CHOP, and prolonged eIF2α phosphorylation, even though the statistics of the latter effect were only borderline significant.

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did not reach statistical significanceno p-value reported

The impact of guanabenz treatment on EHTs during exposure to different ER stressors was modest and did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.