In many cases, the improvements in SN and PPV were quite significant (0.4 ~ 0.8), which shows that the proposed scheme can often find an accurate sequence alignment even when the pair-HMM has difficulty aligning the sequences.
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In many cases, the improvements in SN and PPV were quite significant (0.4 ~ 0.8), which shows that the proposed scheme can often find an accurate sequence alignment even when the pair-HMM has difficulty aligning the sequences.