The amounts of Mfn and Miro tended to increase in aged PINK1 -deficient flies; however, these increases did not reach statistical significance when compared with levels in normal flies expressing β-galactosidase ( PINK1 -/- ; LacZ vs . control in Figure S1 ).
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PINK1-mediated phosphorylation of Parkin boosts Parkin activity in Drosophila.
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