Synergy of combined tPA-edaravone therapy in experimental thrombotic stroke.

PLoS One · 2014 · PMC4049665 · PMID 24911517

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showed a trendp = 0.40not close (p > 0.1)

When edaravone was added to tPA-treatment at 1 h (E + tPA 1 h), the mortality rate was similar to those received tPA alone (27.7%), but the infarct size showed a trend of further reduction (15.5%, p = 0.40 compared to the tPA-treatment alone).

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