Heart failure in patients with chronic kidney disease: a systematic integrative review.

Biomed Res Int · 2014 · PMC4052068 · PMID 24959595

Europe PMC DOI

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did not reach statistical significanceno p-value reported

In patients with the lowest eGFR (< 55.5 mL/min per 1.73 m 2 ), the primary end-point was reduced by 19%, although this did not reach statistical significance.

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highly significantno p-value reported

The trial was stopped prematurely, after a mean follow-up of 1.3 years, as bisoprolol treatment led to a highly significant reduction in all-cause mortality.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.