Although the combination appeared more active than the sum of the two agents alone in the TNBC/basal B cell line MB157, these data did not reach statistical significance, in part because of the high sensitivity to TRAIL alone in this cell line.
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Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening.
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