Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

PLoS One · 2014 · PMC4055488 · PMID 24922517

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0810

boldest claim

The sentences

nominally significantp = 4.6×10 −12actually significant

Furthermore, the number of independent nominally significant loci at Stage 2 (N = 60, (13.5%)) was significantly greater than expected by chance (p = 4.6×10 −12 ).

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a trend towards significancep = 0.081so close (0.05 < p ≤ 0.1)

Under this conditional analysis ZNF3 gene does not show significant association, however NDUFS3 still shows a trend towards significance (p = 0.081) (see Table S8 for details).

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