Acute heat-evoked temperature sensation is impaired but not abolished in mice lacking TRPV1 and TRPV3 channels.

PLoS One · 2014 · PMC4055713 · PMID 24925072

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slightly significantno p-value reported

However, in this background, V1V3dKO mice displayed a slightly significant higher number of jumps in comparison to their WT littermates (119.75±16.86 jumps for V1V3dKO versus 66.33±8.5 for WTs) ( Fig. 5F ), suggesting that loss of TRPV3 in TRPV1-KO background significantly decreased the massive escape behavior observed in TRPV1-KO mice.

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