Serum concentrations of Ang-1, an endothelial barrier-stabilizing factor, were higher in patients with non-complicated FN (1,220.0 pg/ml, range 32.5 to 47,924.0 pg/ml) than in patients with septic shock (898.8 pg/ml, range 77.9 to 5,420.0 pg/ml), although this difference did not reach statistical significance (Mann-Whitney test, P = 0.07) (Figure 2 ).
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A high angiopoietin-2/angiopoietin-1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia.
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