Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer.

3E ); this difference in outcomes was highly significant (p=0.0079; Fisher exact test).

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Tumor sections stained for MMP9 protein expression showed a trend of lower overall stain intensity in the MMP9 KD group, although there was considerable variation within each group (Fig. 4A,B ), suggesting that the knockdown was not uniformly maintained throughout the latter part of the 11 week experimental time course.

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