White pepper and piperine have different effects on pharmacokinetics of puerarin in rats.

Evid Based Complement Alternat Med · 2014 · PMC4058586 · PMID 24991227

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did not reach statistical significanceno p-value reported

However, the difference in T max⁡ , V d , and t 1/2 between groups did not reach statistical significance, except CL was significantly decreased to 58% by pretreatment with 20 mg/kg of piperine.

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