Angiotensin receptor type 1 and endothelin receptor type A on immune cells mediate migration and the expression of IL-8 and CCL18 when stimulated by autoantibodies from systemic sclerosis patients.

Arthritis Res Ther · 2014 · PMC4060229 · PMID 24612997

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highly significantno p-value reported

In addition, IL-8 concentrations revealed a highly significant negative correlation with the time since onset of pulmonary arterial hypertension (PAH) (Figure 6 C).

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did not reach statistical significanceno p-value reported

The numbers of T cells that migrated toward SSc-IgG was higher compared with HD-IgG, but this difference did not reach statistical significance.

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