Barely Significant
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IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis.

Arthritis Res Ther · 2013 · PMC4060232 · PMID 23705835

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showed a trendno p-value reported
A comparison of the levels of IgG1 with those of IgG3 in the same serum sample ( n = 39) against human HSP60 from 2006 showed a trend toward an inverse correlation (r = -0.2).

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