We examined the methylation levels of the four genes in human AML samples and observed significant hypermethylation compared to healthy granulocytes and CD34+ cells in HES6 , ITPKA and TAL1 , while BCOR showed a trend towards hypermethylation in a subgroup of AML patients (Figure 5 ).
← all excerpts
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
1
—
—