Quantitative intratumoural microdistribution and kinetics of (131)I-huA33 antibody in patients with colorectal carcinoma.

This stratification revealed that patients whose tumours were macroscopically viable in both the centre and the periphery had minimal difference in uptake between regions (4.12 ± 0.212 × 10 −3 %ID/g vs 5.39 ± 2.63 × 10 −3 %ID/g, p value not available due to limited patient numbers), whereas patients whose tumours had necrotic centres showed a trend towards less uptake in the tumour centres than the tumour periphery, though this was not significantly different (0.606 ± 0.493 × 10 −3 %ID/g vs 2.98 ± 2.17 × 10 −3 %ID/g, p = 0.06).

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