Gene expression profiles associated with acute myocardial infarction and risk of cardiovascular death.

Gene enrichment analysis was performed with the ToppGene Suite [ 27 ], and showed a highly significant enrichment (hypergeometric P = 4 × 10 -8 ) for 18 genes annotated to the set of 222 genes known to be up-regulated in CD133 + relative to CD133 - hematopoietic stem cells in the 'Jaatinen_HSC_Dn' Molecular Signatures Database (MSigDB) [ 28 ] entry.

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Univariate predictors of cardiovascular death indicated in Table 2 were age, low density lipoprotein, total cholesterol, serum creatinine, AMI, white blood cell count, presence of significant CAD >50%, left ventricular ejection fraction, and PC1 score, with hypertension trending towards significance.

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