Although not significant, antigen-specific cytokine levels showed a trend to a decrease of IL-4 production by CD1d −/− LN cells than wild type counterparts and to an increase of IL-4 production in the C57BL/6 mice which had received αGalCer analog PBS57 ( Figure 3G ).
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Immune modulating effects of NKT cells in a physiologically low dose Leishmania major infection model after αGalCer analog PBS57 stimulation.
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