The association of angiotensin-converting enzyme with biomarkers for Alzheimer's disease.

Miners and colleagues previously showed a trend of divergence between ACE levels and activity in postmortem CSF, but this was not significant and the patterns observed may have been an artifact of postmortem delay where additional changes to the ACE may have occurred post mortem [ 22 ].

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Serum ACE measures and cerebrospinal fluid biomarkers In the total population, higher serum ACE protein level was associated with higher CSF Aβ (borderline significance), but not with CSF tau or ptau levels (Table 2 ).

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