showed a trendp=0.16
Since the study of Katz et al used a higher dosage than the other included studies, after its exclusion, the pooling result showed a trend favouring daptomycin (five RCTs, 638 patients, OR=1.39, 95% CI 0.88 to 2.19, p=0.16, I 2 =0; figure 2 D).