Compared with Smp30 Y/+ Sod1 −/− , hepatic TBARS were higher in Smp30 Y/− Sod1 −/− mice, although the differences did not reach statistical significance ( p = 0.12). 2.4 Increased superoxide anion radical in liver sections from Smp30 Y/− Sod1 −/− male mice To evaluate superoxide anion radicals in livers from Smp30 Y/− Sod1 −/− mice, DHE staining was conducted using frozen liver sections.
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Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis.
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0.1200