The roles of individual mammalian argonautes in RNA interference in vivo.

PLoS One · 2014 · PMC4081796 · PMID 24992693

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a clear trendno p-value reported

A clear trend towards Fads1 mRNA level recovery in Ago3 −/− animals further supports the involvement of Ago3 in siRNA-mediated 3′UTR-targeted knockdown.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.