Dynamic conduction and repolarisation changes in early arrhythmogenic right ventricular cardiomyopathy versus benign outflow tract ectopy demonstrated by high density mapping & paced surface ECG analysis.

Quantification of regional and local conduction delay Differences in slowest measured activation gradient (a measure of slowest endocardial conduction in sinus rhythm) between groups did not reach statistical significance, although activation gradients in ARVC and RVOT ectopy groups were 20% lower than controls (definite ARVC 0.41±17 mm/ms, probable ARVC 0.41±18 mm/ms, RVOT ectopy 0.40±16 mm/ms, Normals 0.51±13 mm/ms, all p>0.05). r 2 , a measure of uniformity of conduction, was higher in both ARVC groups and in normal controls than in the RVOT ectopy patients (definite ARVC: 0.94±0.07, probable ARVC 0.94±0.05, RVOT ectopy 0.85±0.12, Normals:0.94±0.07, p<0.05 vs RVOT ectopy).

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