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Gamma Knife radiosurgery to four or more brain metastases in patients without prior intracranial radiation or surgery.

Cancer Med · 2014 · PMC4101747 · PMID 24510602

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showed a trendno p-value reported
On univariate analysis, total tumor volume ≥3 cc ( P = 0.02) was associated with worsened overall survival and male gender ( P = 0.07) showed a trend suggesting association.

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