Median OS was not reached for the abiraterone group in the final analysis; the OS was 27.2 months for the placebo group and there was a 25% decrease in the risk of death in the abiraterone group, which showed a trend toward OS improvement.
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New developments in the treatment of castration resistant prostate cancer.
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This study had borderline significance in rejecting the null hypothesis, indicating that there may be cross-resistance between abiraterone and docetaxel, which may be due to docetaxel's effect on AR signaling.