Similarly, analysis of 501 ovarian patients revealed that serous tumors with moderate to high levels of Sulf1 (127 of 186, 68%) showed a trend toward improved survival as assessed by Kaplan–Meier survival analysis and log-rank test ( 123 ).
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The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.
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