Substituted N-(biphenyl-4'-yl)methyl (R)-2-acetamido-3-methoxypropionamides: potent anticonvulsants that affect frequency (use) dependence and slow inactivation of sodium channels.

Similarly, the traces for ( R )- 7 and ( R )- 8 (Figure 4 C,D) suggested frequency (use) inhibition of the Na + currents at a 10 μM concentration, but the values did not reach statistical significance.

also in 111,027 other papers