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Epidithiodiketopiperazines (ETPs) exhibit in vitro antiangiogenic and in vivo antitumor activity by disrupting the HIF-1α/p300 complex in a preclinical model of prostate cancer.

Mol Cancer · 2014 · PMC4113146 · PMID 24775564

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VEGF expression decreased with 250 nM gliotoxin but did not reach statistical significance (Figure 4 ; top panel) .

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