Apoptotic lymphocytes of H. sapiens lose nucleosomes in GC-rich promoters.

PLoS Comput Biol · 2014 · PMC4117428 · PMID 25077608

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a negative trendno p-value reported

At the same time, promoters of genes with a negative trend of expression during apoptosis had a similar number of nucleosomes to those in CD4 + cells in normal conditions ( Fig. 4a ).

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a positive trendno p-value reported

We found that promoters of genes with a positive trend of expression had much less nucleosomes during apoptosis than they had in CD4 + cells under normal conditions ( Fig. 4b ).

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