Lipid-laden partially-activated plasmacytoid and CD4(-)CD8α(+) dendritic cells accumulate in tissues in elderly mice.

Immun Ageing · 2014 · PMC4118209 · PMID 25089147

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an increasing trendno p-value reported

MHC class-I expression significantly increased on pDCs in elderly-derived livers and showed an increasing trend in elderly-derived lungs, but did not change in spleens, mesLNs, supLNs and axLNs (Figure 3 B).

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did not reach statistical significanceno p-value reported

Similar trends were seen in the pDC and CD4 - CD8α + DC subsets when expressed as cells/mg, although the differences did not reach statistical significance (Additional file 1 : Figure S1E).

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