Barely Significant
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Conventional hemodynamic resuscitation may fail to optimize tissue perfusion: an observational study on the effects of dobutamine, enoximone, and norepinephrine in patients with acute myocardial infarction complicated by cardiogenic shock.

PLoS One · 2014 · PMC4118994 · PMID 25084171

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Using standard heart failure treatment, including diuretics, ACE-inhibitors, and betablockers, they reported a decrease in parameters of neurohumoral activation together with an increase in microvascular flow index, but correlations between changes in neurohormones and changes in microcirculation did not reach statistical significance.

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