Toll-like receptor 4 upregulation by angiotensin II contributes to hypertension and vascular dysfunction through reactive oxygen species production.

PLoS One · 2014 · PMC4122400 · PMID 25093580

Europe PMC DOI

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0.0680

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0.0680

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did not reach statistical significanceP = 0.068so close (0.05 < p ≤ 0.1)

The heart weight:tibia length ratio was greater in SHRs (0.346±0.022) as compared with Wistar rats (0.294±0.009), although the differences did not reach statistical significance (P = 0.068); treatment of SHR with anti-TLR4 antibody did not affect this ratio (0.346±0.009, P>0.05).

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