Interestingly, even if not statistically different, there was a lower amount of IL-1 β in frozen PRP with respect to that of fresh PRP (14.4 pg/mL versus 70.1 pg/mL, resp.), and a significant trend of a further increase of IL-1 β from 1 hour to 7 days was observed only in fresh PRP.
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Does platelet-rich plasma freeze-thawing influence growth factor release and their effects on chondrocytes and synoviocytes?
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