Retrospective analysis of the safety and efficacy of high-dose interleukin-2 after prior tyrosine kinase inhibitor therapy in patients with advanced renal cell carcinoma.

J Immunother · 2014 · PMC4127096 · PMID 25075565

Europe PMC DOI

hedged sentence

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

did not reach statistical significanceP =0.064so close (0.05 < p ≤ 0.1)

The association between number of doses received and cardiac toxicity did not reach statistical significance, with P =0.064 for all-grade cardiac toxicity, and P =0.076 for grades ≥3 cardiac toxicity.

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