Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.

Biomed Res Int · 2014 · PMC4131462 · PMID 25147816

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PEGPH20 treatment showed a trend (2.3-fold) to increase CC3-positive cells in BxPC-3 HAS3 tumors but had no effect in BxPC-3 tumors ( Figure 6(a) ).

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