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Lymphocyte Activation Gene-3 (LAG-3) negatively regulates environmentally-induced autoimmunity.

PLoS One · 2014 · PMC4133201 · PMID 25122007

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We observed that Lag-3 −/− mice developed a greater concentration of serum IgG1 and IgE immunoglobulins than the wild-type controls although the differences did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.