Quantification of blood vessel density with CD31 staining showed a trend towards higher vascularisation of MMTV-PyVmT; Abcc10 +/+ tumours, and Caspase 3 staining indicated a higher rate of apoptosis in wild-type tumours compared with Abcc10 null tumours ( Figure 2C ).
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Abcc10 status affects mammary tumour growth, metastasis, and docetaxel treatment response.
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