Based on the standard mentioned above, GUA~A, AGC~A, AAG~C, AGA~C, A~GUA, U~AGC, U~AAG, C~AAG, G~AGA, and U~AUG have a strong trend to exist in the helix of PRRSV nsp1 α gene and UUA~A, AUA~G, GUG~U, UCA~C, ACA~C, UAC~U, UAC~C, CAU~G, CGC~U, G~UUA, U~GUG, U~UCA, C~AGU, C~ACA, G~UAC, U~CAU, and U~CGC have a strong tendency to exist in the β -strand of the nsp1 α gene. 4.
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The effects of the context-dependent codon usage bias on the structure of the nsp1α of porcine reproductive and respiratory syndrome virus.
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In detail, the codons with N 1 context or 1 N context (GUA~A, AGC~A, AAG~C, AGA~C, A~AUA, U~AGC, U~AAG, C~AAG, G~AGA, and U~AUG) have an obvious trend to exist in the helix unit of the nsp1 α .