Role of proinflammatory cytokines on expression of vitamin D metabolism and target genes in colon cancer cells.

J Steroid Biochem Mol Biol · 2014 · PMC4138205 · PMID 24120915

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highly significantno p-value reported

After 24 h the effect of TNFα alone became highly significant, reducing CYP27B1 levels to 46% of the vehicle control.

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did not reach statistical significanceno p-value reported

TNFα upregulated CYP24A1 expression 1.7-fold after 6 h, however, the increase did not reach statistical significance ( Fig. 1 A).

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