PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia.

Comparison of the KC mice with age-matched littermate control mice led to the observation that the pancreatic expression of PD2/Paf1 mRNA at 10 and 20 weeks age appeared to have decreased in the Kras mice compared to the normal mice, even though that decrease did not reach statistical significance.

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