Relationship of cortisol levels and genetic polymorphisms to antidepressant response to placebo and fluoxetine in patients with major depressive disorder: a prospective study.

BMC Psychiatry · 2014 · PMC4149200 · PMID 25086452

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

almost significantp = 0.056so close (0.05 < p ≤ 0.1)

This difference was almost significant and the trauma history could be related to poorer response (p = 0.056, calculated by chi-square test).

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approached significancep = 0.057so close (0.05 < p ≤ 0.1)

In a more detailed analysis dividing the group that continued the treatment into “abandoned between the third and eighth week” and “completed treatment” the results approached significance (p = 0.057, general linear model for repeated measures) (Figure 2 E).

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borderline significanceno p-value reported

CRHR2 polymorphisms have been associated with increased risk of suffering major depression with borderline significance [ 17 , 58 ] and with a worse overall response to citalopram (SSRI) [ 17 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.