Long-term low carbohydrate diet leads to deleterious metabolic manifestations in diabetic mice.

PLoS One · 2014 · PMC4149431 · PMID 25170869

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did not reach statistical significanceno p-value reported

In these mice, the downregulation of insulin signaling due to insulin deficiency or insulin resistance may blunt fatty acid synthesis, which may explain why the body or fat weight changes in these diabetic mice did not reach statistical significance.

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