ER β cx positivity in SLN lymphocytes was more common in node-positive than node-negative patients (57 out of 125 (45.6%) vs 59 out of 167 (35.3%)), even though this did not reach statistical significance ( P =0.076).
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Oestrogen receptors β1 and βcx have divergent roles in breast cancer survival and lymph node metastasis.
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0.0760
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Conclusions: Our study reveals highly significant although antagonising roles of ER β 1 and ER β cx in breast cancer.