The nine DHSs reaching modest significance in the ileum were not near any gene known to be regulated by microbiota (Supplemental Table S7; Rawls et al. 2006 ; Donohoe et al. 2011 ; El Aidy et al. 2012 ; Larsson et al. 2012 ; Pott et al. 2012 ).
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Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape.
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