Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder.

Front Cell Neurosci · 2014 · PMC4161165 · PMID 25309317

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0800

boldest claim

The sentences

highly significantP < 0.001actually significant

There was a highly significant main effect of ganaxolone treatment on aggressive behavior ( F 4,36 = 6.89, P < 0.001).

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showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

The lowest dose of ganaxolone (3.75 mg/kg) only showed a trend towards improvement of anxiety-like behavior expressed as the ratio of open arm to closed arm total time ( P = 0.08; Figure 3 ).

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