The prevalence of cardiovascular disease risk factors and the Framingham Risk Score in patients undergoing percutaneous intervention over the last 17 years by gender: time-trend analysis from the Mayo Clinic PCI Registry.

J Prev Med Public Health · 2014 · PMC4162120 · PMID 25139168

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a significant trendno p-value reported

A significant trend towards higher body mass index and more prevalent hypercholesterolemia, hypertension, and diabetes was found over time.

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an increasing trendno p-value reported

BP and lipid profiles improved for the patients who received a PCI most recently ( p for trend<0.001); however, body mass index (BMI), hypercholesterolemia, hypertension, and DM showed an increasing trend ( p for trend<0.001).

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a decreasing trendno p-value reported

In this study, we revealed a decreasing trend for the FRS and 10-year CVD risk over time, likely due to the significant decrease in BP and increase in HDL-C as a result of medication effects or therapeutic interventions.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.